Non-Markovian dynamics of reaction coordinate in polymer folding
نویسندگان
چکیده
منابع مشابه
Non-Markovian polymer reaction kinetics.
Describing the kinetics of polymer reactions, such as the formation of loops and hairpins in nucleic acids or polypeptides, is complicated by the structural dynamics of their chains. Although both intramolecular reactions, such as cyclization, and intermolecular reactions have been studied extensively, both experimentally and theoretically, there is to date no exact explicit analytical treatmen...
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The non-Markovian nature of polymer motions is accounted for in folding kinetics, using frequencydependent friction. Folding, like many other problems in the physics of disordered systems, involves barrier crossing on a correlated energy landscape. A variational transition state theory that reduces to the usual Bryngelson-Wolynes Kramers approach when the non-Markovian aspects are neglected is ...
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The exact stochastic decomposition of non-Markovian dissipative quantum dynamics is combined with the time-dependent semiclassical initial value formalism. It is shown that even in the challenging regime of moderate friction and low temperatures, where non-Markovian effects are substantial, this approach allows for the accurate description of dissipative dynamics in anharmonic potentials over m...
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ژورنال
عنوان ژورنال: Soft Matter
سال: 2017
ISSN: 1744-683X,1744-6848
DOI: 10.1039/c7sm00395a