Noninvasive Measurement of Cerebral Blood Flow With99mTc-Hexamethylpropyleneamine Oxime Single-Photon Emission Computed Tomography and 1-Point Venous Blood Sampling

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Noninvasive measurement of cerebral blood flow with (99m)Tc-hexamethylpropyleneamine oxime single-photon emission computed tomography and 1-point venous blood sampling.

BACKGROUND AND PURPOSE The arterial and venous blood concentration of technetium 99m-labeled hexamethylpropyleneamine oxime ((99m)Tc-HMPAO) reaches an equilibration more rapidly than other CBF tracers. We hypothesized that (99m)Tc radioactivity of a venous sample at equilibrium, which is similar to that of an arterial sample, would allow estimation of the integrated input function for the clini...

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Abnormal cerebral blood flow in methamphetamine abusers assessed by brain perfusion single emission computed tomography

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Effects of aging on regional cerebral blood flow assessed by using technetium Tc 99m hexamethylpropyleneamine oxime single-photon emission tomography with 3D stereotactic surface projection analysis.

OBJECTIVES Although many previous reports have described age-related changes in regional cerebral blood flow (rCBF), none has used 3D stereotactic surface projection (3D-SSP) analysis, which is able to detect subtle and significant changes in rCBF. METHODS The subjects were 31 healthy volunteers (16 men and 15 women; 50-79 years of age) without abnormal MR imaging and MR angiographic findings...

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abnormal cerebral blood flow in methamphetamine abusers assessed by brain perfusion single emission computed tomography

introduction:amphetamines are central nervous system (cns) stimulant substances and amphetamine abuse is considered a growing problem in our country. previous studies revealed destructive effects of amphetamines on metabolism, perfusion and structure of brain. the aim of current study was evaluating regional cerebral blood flow (rcbf) disturbances in methamphetamine (ma) abusers using brain per...

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ژورنال

عنوان ژورنال: Stroke

سال: 2000

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.31.9.2203