Nonlinear optical microscopy of articular cartilage
نویسندگان
چکیده
منابع مشابه
Nonlinear optical microscopy of articular cartilage.
OBJECTIVE To assess the ability of nonlinear optical microscopy (NLOM) to image ex vivo healthy and degenerative bovine articular cartilage. METHOD Fresh bovine femoral-tibial joints were obtained from an abattoir. Articular cartilage specimens were harvested from the tibial plateau. Normal and degenerative specimens were imaged by NLOM and subsequently fixed and processed for histological ex...
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Few previous studies have been made of the appearance of articular cartilage under the electron microscope. Cameron and Robinson (1958) examined the matrix of both articular and epiphysial cartilages in femora of infants who had died in the neonatal period. No observations were made upon the cells as they were unable to assess the extent of post mortem change. They described the presence in the...
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It has long been recognized that the power of articular cartilage to regenerate and repair wounds in its substance is feeble or nonexistent (Hunter, 1743; Paget, 1853). This is largely due to the fact that chondrocytes in the mature animal are virtually incapable of mitotic division (Elliot, 1936; Mankin, 1962a,b, 1963). It is now believed that superficial injuries (partial-thickness defects) w...
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Articular cartilage (AC) is a type of hyaline covering material for the articulating ends of bones of synovial joints which transmits high loads and maintains contact stresses at an acceptably low level. There have been numerous studies focusing on the assessment of the AC degeneration. The measures which have been utilized to evaluate the level of AC degeneration include morphology, wear parti...
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High-resolution microscopy methods based on different nonlinear optical (NLO) contrast mechanisms are finding numerous applications in biology and medicine. While the basic implementations of these microscopy methods are relatively mature, an important direction of continuing technological innovation lies in improving the throughput of these systems. Throughput improvement is expected to be imp...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2005
ISSN: 1063-4584
DOI: 10.1016/j.joca.2004.12.007