NOTCH2 Is Neither Rearranged nor Mutated in t(1;19) Positive Oligodendrogliomas
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چکیده
منابع مشابه
NOTCH2 Is Neither Rearranged nor Mutated in t(1;19) Positive Oligodendrogliomas
The combined deletion of 1p and 19q chromosomal arms is frequent in oligodendrogliomas (OD) and has recently been shown to be mediated by an unbalanced t(1;19) translocation. Recent studies of 1p/19q co-deleted OD suggest that the NOTCH2 gene is implicated in oligodendrocyte differentiation and may be involved in this rearrangement. The objective of the present study was to analyze the NOTCH2 l...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2009
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0004107