Nucleotide binding to actin. Cation dependence of nucleotide dissociation and exchange rates.
نویسندگان
چکیده
منابع مشابه
Nucleotide binding to actin. Cation dependence of nucleotide dissociation and exchange rates.
We have reinvestigated nucleotide binding to actin in order to resolve conflicts regarding the mechanism of nucleotide dissociation and exchange. We present evidence that supports a mechanism for nucleotide binding to actin in which the tightly bound divalent cation (Ca2+ or Mg2+) directly interacts with the bound nucleotide. The dissociation rates of ATP or ADP from actin are limited by the di...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1993
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)52929-x