Nucleotide Sequences Derived from Pheasant DNA in the Genome of Recombinant Avian Leukosis Viruses with Subgroup F Specificity

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Nucleotide sequences derived from pheasant DNA in the genome of recombinant avian leukosis viruses with subgroup F specificity.

Recombination between viral and cellular genes can give rise to new strains of retroviruses. For example, Rous-associated virus 61 (RAV-61) is a recombinant between the Bryan high-titer strain of Rous sarcoma virus (RSV) and normal pheasant DNA. Nucleic acid hybridization techniques were used to study the genome of RAV-61 and another RAV with subgroup F specificity (RAV-F) obtained by passage o...

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Widespread presence, in chickens, of DNA complementary to the RNA genome of avian leukosis viruses.

DNA-RNA hybridization experiments have demonstrated the widespread presence in chickens of DNA complementary to the RNA of avian myeloblastosis virus. All apparently normal chicken embryos, or adult chickens that were tested, contained viral DNA in amounts ranging from 1.7 to 4.6 viral genome equivalents per cell. Embryos that were negative or positive for the group-specific antigen of avian le...

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Proliferative fibromatosis in avian skeletal muscle caused by cloned recombinant avian leukosis viruses.

Two molecular recombinants (EU-8 and K-3) constructed from ring-necked pheasant virus and UR2AV, the helper virus associated with avian sarcoma virus UR2, caused a high incidence of a hitherto unreported pathological condition in chick skeletal muscle. A disease spectrum was observed in which muscle was infiltrated by proliferating fibroblasts and caused white streaks, white diffuse areas, or w...

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Radioimmunoassay for the envelope glycoprotein of subgroup E avian leukosis-sarcoma viruses.

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 1977

ISSN: 0022-538X,1098-5514

DOI: 10.1128/jvi.24.2.505-513.1977