O29 Short term outcome study of systemic sclerosis with pulse cyclophosphamide

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Systemic sclerosis and dexamethasone cyclophosphamide pulse therapy.

Sir, There have been quite a few instances where the physician or may be even a dermatologist (mis) advices a patient having systemic sclerosis that there is no satisfactory treatment for this disease, as has also been done in the paper ‘Therapeutic trials for systemic sclerosis: An update’ by Sardana and Garg.[1] Such patients often feel frustrated and disappointed, till another dermatologist ...

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Intravenous Cyclophosphamide Pulse Therapy in the Treatment of Systemic Sclerosis-Related Interstitial Lung Disease: A Long Term Study

OBJECTIVE Interstitial lung disease (ILD) frequently complicates systemic sclerosis (SSc). Cyclophosphamide (CYC) is a promising immunosuppressive therapy for SSc-related ILD. Our objective was to investigate the effectiveness of an intravenous CYC (iv CYC) pulse regime in SSc-related ILD during treatment and thereafter. METHODS In a prospective observational study ten consecutive patients wi...

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COMBINATION THERAPY WITH PULSE CYCLOPHOSPHAMIDE PLUS CORTICOSTEROIDS IMPROVES RENAL OUTCOME IN PATIENTS WITH LUPUS NEPHRITIS

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Cyclophosphamide in systemic sclerosis: light and shadows.

© Copyright CLINICALAND EXPERIMENTAL RHEUMATOLOGY 2004. Pulmonary interstitial fibrosis (PIF) affects half of all patients with systemic sclerosis (SSc) (1) and accounts for one-third of SSc-related deaths (2). Despite enormous efforts, therapy remains empirical and its efficacy is questionable. D-penicillamine (3) interfero n -γ (4), and cyclophosphamide (5) have been used to halt the progress...

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ژورنال

عنوان ژورنال: Indian Journal of Rheumatology

سال: 2008

ISSN: 0973-3698

DOI: 10.1016/s0973-3698(10)60403-7