O32 Ontogeny of human kidney OCT2 expression across the paediatric age range
نویسندگان
چکیده
منابع مشابه
Kidney-specific expression of human organic cation transporter 2 (OCT2/SLC22A2) is regulated by DNA methylation.
Human organic cation transporter 2 (OCT2/SLC22A2), which is specifically expressed in the kidney, plays critical roles in the renal secretion of cationic compounds. Tissue expression and membrane localization of OCT2 are closely related to the tissue distribution, pharmacological effects, and/or adverse effects of its substrate drugs. However, the molecular mechanisms underlying the kidney-spec...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 2019
ISSN: 0003-9888,1468-2044
DOI: 10.1136/archdischild-2019-esdppp.32