OP42 Increasing Access To Real-World Data To Move From Health Technology Assessment To Health Technology Management

Introduction When assessing existing or emerging technologies using a one-off health technology assessment (HTA) we do not take into consideration the effects on people who will receive once approved. Developments in real-world data (RWD) can help to address this by moving ongoing management (HTM). Methods To move HTM, first need develop HTM requirements. We undertook user interviews with National Institute for Health and Care Excellence (NICE) HTA developers list of surveyed types that NICE currently has access performed gap analysis understand where further is needed. then worked external systems partners identify review available sources could support HTM. Results From our established eight Data needed be linked, cover full care pathways, contain from new collections, shareable, have direct access, high quality, comprehensive coverage, responsive technological developments (such as artificial intelligence). The revealed fragmented landscape United Kingdom (UK). identified Service Digital’s (NHSD) Trusted Research Environment main source This addresses challenges providing approved researchers timely secure range linked data. also large national collection would capture all technologies, such orphan rare conditions. therefore process accessing smaller collections disease specific registries. how use data, developed Real-World Evidence (RWE) Framework provides clear guidance expectations planning, conduct, reporting, appraisal RWE studies. Conclusions requirements type deliver well several suitable meet these