Open Reading Frame Phylogenetic Analysis on the Cloud
نویسندگان
چکیده
منابع مشابه
Open Reading Frame Phylogenetic Analysis on the Cloud
Phylogenetic analysis has become essential in researching the evolutionary relationships between viruses. These relationships are depicted on phylogenetic trees, in which viruses are grouped based on sequence similarity. Viral evolutionary relationships are identified from open reading frames rather than from complete sequences. Recently, cloud computing has become popular for developing intern...
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A plasmid was constructed that facilitates the cloning and expression of open reading frame DNA. A DNA fragment containing a bacterial promoter and the amino terminus of the cI gene of bacteriophage lambda was fused to an amino-terminally deleted version of the lacZ gene. An appropriate cloning site was inserted between these two fragments such that a frameshift mutation was introduced upstream...
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During translation, a string of non-overlapping triplet codons in messenger RNA is decoded into protein. The ability of a ribosome to decode mRNA without shifting between reading frames is a strict requirement for accurate protein biosynthesis. Despite enormous progress in understanding the mechanism of transfer RNA selection, the mechanism by which the correct reading frame is maintained remai...
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References 1 Gething, M. J. and Sambrook, J. (1992) Nature 355, 33-45 2 Lewis, M. J. and Pelham, H. R. B. (1992) Cell 68, 353-364 3 Kaiser, C. A. and Schekman, R. (1990) Cell 61, 723-733 4 Bennett, M. K., Calakos, M. and Scheller, R. H. (1992) Science 257, 255-259 5 Rothman, J. E. and Orci, L. (1992) Nature 355, 409-415 6 Quinn, P., Griffiths, G. and Warren G. (1984) J. Cell BioL 98, 2142-2147 ...
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The endmost chromosome I ORF is silenced by a natural telomere position effect. YAR073W/IMD1 was found to be transcribed at much higher levels in sir3 mutants and when its adjacent telomere was removed from it. These results suggest that telomeres play a role in silencing actual genes.
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ژورنال
عنوان ژورنال: International Journal of Genomics
سال: 2013
ISSN: 2314-436X,2314-4378
DOI: 10.1155/2013/614923