Opioid-free Anesthesia for Laparoscopic Gastroplasty. A Prospective and Randomized Trial

Background: Opioid-free anesthesia (OFA) has gained popularity in recent years due to concerns about the abusive use of this drug but also potential benefits OFA for pain control and decreased side effects. Objectives: This trial aimed study whether opioid-free patients submitted laparoscopic gastroplasty compared with fentanyl. The primary objective was measure score morphine rescue analgesia. secondary evaluate incidence postoperative nausea vomiting (PONV) oxygen desaturation. Methods: Patients undergoing were randomized receive general fentanyl (n = 30) or according a predefined protocol. They assessed using verbal numerical scale (VNS), consumption PONV post-anesthesia care unit on first day after surgery. Besides, desaturation during immediate period recorded. blinded surgeon evaluators. Results: groups comparable all demographic data analyzed. A significance level 5% used, no differences found variables studied. Conclusion: specific protocol presented safe effective. However, did not find any benefit it videolaparoscopic gastroplasties.