Opioid receptors at adrenergic nerve terminals in rabbit ear artery
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چکیده
منابع مشابه
cAMP-dependent facilitation of glutamate release by beta-adrenergic receptors in cerebrocortical nerve terminals.
We have investigated the presence of a cAMP-protein kinase A-dependent pathway in cerebrocortical nerve terminals and its role in the modulation of glutamate release. The activation of adenylyl cyclase with forskolin enhances intrasynaptosomal cAMP and induces Ca2+-dependent glutamate release. The membrane permeant analogue dibutyryl cAMP mimics this facilitatory effect, whereas the inactive co...
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Sympathetic nerve stimulation and intralummal norepinephrine infusion for more than 15 seconds produced a biphasic response in the isolated rabbit ear artery perfused with RREBS solution. This response consisted of an initial rapid constriction (phase A), which was followed by partial relaxation, and a final slowly developing constriction (phase B), which lasted for the duration of nerve stimul...
متن کاملComparison of constrictor responses of the rabbit ear artery to norepinephrine and to sympathetic nerve stimulation.
The perfused isolated rabbit ear artery was used as a vascular model to compare the constrictor responses to exogenous and endogenous norepinephrine. The aim of the study was to estimate the concentrations of norepinephrine reaching the smooth muscle of the artery during sympathetic nerve stimulation. The artery was perfused so that exogenous norepinephrine was introduced exclusively from the a...
متن کاملComparison of Constrictor Responses of the Rabbit Ear Artery to Noreplnephrine and to Sympathetic Nerve Stimulation
The perfused isolated rabbit ear artery was used as a vascular model to compare the constrictor responses to exogenous and endogenous norepinephrine. The aim of the study was to estimate the concentrations of norepinephrine reaching the smooth muscle of the artery during sympathetic nerve stimulation. The artery was perfused so that exogenous norepinephrine was introduced exclusively from the a...
متن کاملPharmacological characterization of the "silent" 5-hydroxytryptamine1B-like receptors of rabbit ear artery.
Serotonin acts on 5-hydroxytryptamine (5-HT)1B-like receptors in isolated rabbit ear artery precontracted with phenylephrine (PHE). These receptors are inactive, or "silent," in untreated vessels. Ear artery rings were mounted in tissue baths for the measurement of isometric contraction to further characterize these 5-HT1B-like receptors. The 5-HT1-selective receptor agonist sumatriptan failed ...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1985
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)63855-2