Optic Disc Dose Comparison Between 125I and 103Pd Collaborative Ocular Melanoma Study (COMS) Plaques Based on Current Clinical Practice

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Dosimetry Comparison of Water Phantom and Complete Eye Definition for 125I and 103Pd Brachytherapy Plaques

Introduction: In this paper, by complete definition of human eye containing the various parts and their materials, the difference between this model and a homogeneous water phantom are compared for two ophthalmic plaques using 125I and 103Pd. Material and methods: The simulation of the two phantoms were performed in the MCNP-4C code and by using the geometry of a three-dimensional eye, differen...

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Dosimetric benefit of a new ophthalmic radiation plaque.

PURPOSE To determine whether the computed dosimetry of a new ophthalmic plaque, EP917, when compared with the standard Collaborative Ocular Melanoma Study (COMS) plaques, could reduce radiation exposure to vision critical structures of the eye. METHODS AND MATERIALS One hundred consecutive patients with uveal melanoma treated with COMS radiation plaques between 2007 and 2010 were included in ...

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dosimetry comparison of water phantom and complete eye definition for 125i and 103pd brachytherapy plaques

introduction: in this paper, by complete definition of human eye containing the various parts and their materials, the difference between this model and a homogeneous water phantom are compared for two ophthalmic plaques using 125i and 103pd. material and methods: the simulation of the two phantoms were performed in the mcnp-4c code and by using the geometry of a three-dimensional eye, differen...

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103Pd versus 125I ophthalmic plaque brachytherapy: preoperative comparative radiation dosimetry for 319 uveal melanomas

OBJECTIVE This study was conducted to compare the relative, clinical intraocular dose distribution for palladium-103 (103Pd) versus iodine-125 (125I) ophthalmic plaque radiation therapy. METHODS Preoperative comparative radiation dosimetry was performed to evaluate 319 consecutive uveal melanomas treated between 2006 and 2012. RESULTS There were 68 (21.3 %) anterior (iris and/or ciliary bod...

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The Collaborative Ocular Melanoma Study: an overview.

BACKGROUND The Collaborative Ocular Melanoma Study (COMS) is a 3-arm study that includes two multicenter randomized clinical trials designed to compare the effectiveness of brachytherapy to enucleation for treatment of medium-size choroidal melanomas, and the effectiveness of enucleation with and without preoperative external-beam radiotherapy for large choroidal melanomas. The third arm is an ...

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ژورنال

عنوان ژورنال: Cureus

سال: 2021

ISSN: 2168-8184

DOI: 10.7759/cureus.15980