Optical imaging of cortical networks via intracortical microstimulation

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Optical imaging of cortical networks via intracortical microstimulation.

Understanding cortical organization is key to understanding brain function. Distinct neural networks underlie the functional organization of the cerebral cortex; however, little is known about how different nodes in the cortical network interact during perceptual processing and motor behavior. To study cortical network function we examined whether the optical imaging of intrinsic signals (OIS) ...

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Innovative Methodology Optical imaging of cortical networks via intracortical microstimulation

Brock AA, Friedman RM, Fan RH, Roe AW. Optical imaging of cortical networks via intracortical microstimulation. J Neurophysiol 110: 2670 –2678, 2013. First published September 11, 2013; doi:10.1152/jn.00879.2012.—Understanding cortical organization is key to understanding brain function. Distinct neural networks underlie the functional organization of the cerebral cortex; however, little is kno...

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Intracortical microstimulation of bilateral frontal eye field.

We trained two monkeys to perform a fixation task. Intracortical microstimulation (ICMS) was applied to the monkey frontal eye field (FEF) while monkeys were fixating on one of five fixation LEDs. The ICMS was applied in two different manners. Under the single stimulation condition, ICMS was delivered to either right or left FEF. Under the paired stimulation condition, bilateral FEF were succes...

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Auditory cortical activity after intracortical microstimulation and its role for sensory processing and learning.

Several studies have shown that animals can learn to make specific use of intracortical microstimulation (ICMS) of sensory cortex within behavioral tasks. Here, we investigate how the focal, artificial activation by ICMS leads to a meaningful, behaviorally interpretable signal. In natural learning, this involves large-scale activity patterns in widespread brain-networks. We therefore trained ge...

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RAPID COMMUNICATION Intracortical Microstimulation of Bilateral Frontal Eye Field

Fujii, Naotaka, Hajime Mushiake, and Jun Tanji. Intracortical on a front panel separated by 207 from a center LED] for a fixation microstimulation of bilateral frontal eye field. J. Neurophysiol. 79: period of 1.5–2.0 s. Monkeys were rewarded if their eyes remained 2240–2244, 1998. We trained two monkeys to perform a fixation fixated within a 27 fixation window and in each trial, fixation targe...

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ژورنال

عنوان ژورنال: Journal of Neurophysiology

سال: 2013

ISSN: 0022-3077,1522-1598

DOI: 10.1152/jn.00879.2012