Optimal Objective-Based Experimental Design for Uncertain Dynamical Gene Networks with Experimental Error
نویسندگان
چکیده
منابع مشابه
Prediction uncertainty and optimal experimental design for learning dynamical systems.
Dynamical systems are frequently used to model biological systems. When these models are fit to data, it is necessary to ascertain the uncertainty in the model fit. Here, we present prediction deviation, a metric of uncertainty that determines the extent to which observed data have constrained the model's predictions. This is accomplished by solving an optimization problem that searches for a p...
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ژورنال
عنوان ژورنال: IEEE/ACM Transactions on Computational Biology and Bioinformatics
سال: 2018
ISSN: 1545-5963,1557-9964,2374-0043
DOI: 10.1109/tcbb.2016.2602873