Optimization and practical implementation of ultrafast 2D NMR experiments

Implementing ultrafast 2D NMR experiments on a Bruker Avance Spectrometer

Ultrafast solid-state 2D NMR experiments via orientational encoding.

Among the methods proposed in recent years toward the acceleration of multidimensional NMR acquisitions is an "ultrafast" approach, capable of delivering arbitrary 2D correlations within a single scan. This scheme operates by parallelizing the indirect-domain temporal incrementation involved in 2D acquisitions, using as aid an ancillary inhomogeneous frequency broadening acting in combination w...

Line shape considerations in ultrafast 2D NMR.

We have recently proposed and demonstrated an approach that enables the acquisition of 2D nuclear magnetic resonance (NMR) spectra within a single scan. The approach is based on spatially encoding the spins' evolution along the indirect domain with the aid of a magnetic field gradient, and subsequently decoding this information numerous times over the course of the signal acquisition while spin...

Practical Aspects of Quantitative NMR Experiments

This discussion presumes that you already have an understanding of the basic theory of NMR. There are a number of issues that should be considered when measuring NMR spectra for quantitative analysis. Many of these issues pertain to the way that the NMR signal is acquired and processed. It is usually necessary to perform Q-NMR measurements with care to obtain accurate and precise quantitative r...

Multiple ultrafast, broadband 2D NMR spectra of hyperpolarized natural products.

The combination of ex situ dynamic nuclear polarization (DNP) with nuclear magnetic resonance (NMR) leads to signal-to-noise enhancements of 10(3)-10(4) compared to conventional NMR. Ex situ DNP, however, is ill-suited for collecting the array of transients needed in 2D NMR spectroscopy. Spatially encoded single-scan 2D NMR methods can circumvent this drawback, yet these "ultrafast" experiments...