Osteoblast maturation on microtextured titanium involves paracrine regulation of bone morphogenetic protein signaling
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چکیده
منابع مشابه
The extracellular regulation of bone morphogenetic protein signaling.
In many cases, the level, positioning and timing of signaling through the bone morphogenetic protein (BMP) pathway are regulated by molecules that bind BMP ligands in the extracellular space. Whereas many BMP-binding proteins inhibit signaling by sequestering BMPs from their receptors, other BMP-binding proteins cause remarkably context-specific gains or losses in signaling. Here, we review rec...
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Homeostasis Marianna Rodova1, Seunghwan Kim1, M. Abdul Mottaleb2 and M. Rafiq Islam1* 1Biochemistry Laboratory, Northwest Missouri State University, Maryville, Missouri, USA 2Center for Innovation and Entrepreneurship, Northwest Missouri State University, Maryville, Missouri, USA *Corresponding author: Rafiq Islam, Biochemistry Laboratory, Northwest Missouri State University, Maryville, USA, Te...
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Mesenchymal cells can differentiate into osteoblasts, adipocytes, myoblasts, or chondroblasts. Whether mesenchymal cells that have initiated differentiation along one lineage can transdifferentiate into another is largely unknown. Using 3T3-F442A preadipocytes, we explored whether extracellular signals could redirect their differentiation from adipocyte into osteoblast. 3T3-F442A cells expresse...
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The bone morphogenetic proteins (BMPs), as members of the transforming growth factor-beta (TGF-beta) superfamily, not only control bone formation, but also regulate multiple key steps during embryonic development and differentiation. Furthermore, BMPs play critical roles in maintaining the homeostasis of the cardiovascular, pulmonary, reproductive, urogenital, and nervous systems in adult life....
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ژورنال
عنوان ژورنال: Journal of Biomedical Materials Research Part A
سال: 2014
ISSN: 1549-3296,1552-4965
DOI: 10.1002/jbm.a.35308