Osteopontin prevents monocyte recirculation and apoptosis
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چکیده
منابع مشابه
Trahalose Activates Autophagy and Prevents Hydrogen Peroxide-Induced Apoptosis in the Bone Marrow Stromal Cells
Bone marrow stromal stem cells (BMSCs) play a significant role in cell therapy. These cells quickly die after transplantation to the affected area due to oxidative stress. The natural disaccharide, trehalose which can be known as autophagy inducer. The present study aimed to investigate the role of trehalose in preventing BMSCs from oxidative stress caused by H2O2. BMSCs were isolated from the ...
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متن کاملTrahalose Activates Autophagy and Prevents Hydrogen Peroxide-Induced Apoptosis in the Bone Marrow Stromal Cells
Bone marrow stromal stem cells (BMSCs) play a significant role in cell therapy. These cells quickly die after transplantation to the affected area due to oxidative stress. The natural disaccharide, trehalose which can be known as autophagy inducer. The present study aimed to investigate the role of trehalose in preventing BMSCs from oxidative stress caused by H2O2. BMSCs were isolated from the ...
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Peripheral blood monocytes phagocytose and kill pathogens; they are recruited into inflammatory sites and are responsible for triggering the symptoms of sepsis. We focused on the consequences of apoptosis of monocytes, spontaneous or induced, on their function. Monocytes acting as antigen-presenting cells (APC) are eliminated by activated T-cells via the mechanism that triggers their apoptosis....
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Fas is an apoptosis-signaling receptor molecule expressed in vivo on thymocytes, liver, heart, and ovary. In vivo administration of the anti-Fas Jo2 antibody in mice induces severe apoptotic liver damage leading to fulminant hepatitis and death. Linomide, a quinoline 3-carboxamide, inhibits apoptosis of B and T cells induced by various stimuli including viruses, superantigens, and glucocorticoi...
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ژورنال
عنوان ژورنال: Journal of Leukocyte Biology
سال: 2007
ISSN: 0741-5400
DOI: 10.1189/jlb.1106711