Outcomes of anastrozole in oligozoospermic hypoandrogenic subfertile men
نویسندگان
چکیده
منابع مشابه
Definition and current evaluation of subfertile men.
Male infertility affects 10% of reproductive aged couples worldwide and is treatable in many cases. In addition to other well-described etiologies, genetic causes of male infertility are now more commonly diagnosed. Using principles of evidence-based medicine, this review outlines diagnostic and treatments options to inform clinical management. In order of importance, randomized controlled clin...
متن کاملImpact of DNA Damage on the Frequency of Sperm Chromosomal Aneuploidy in Normal and Subfertile Men
Background: Various frequencies of sperm aneuploidy are reported in sperms of subfertile patients compared to normal individuals. Moreover, sperm DNA damage is shown to be associated with male infertility. In this study, the rate of DNA damage and frequencies of aneuploidy in sperms of subfertile patients was investigated. Methods: Semen samples were obtained from healthy normal and subfertile ...
متن کاملAbsence of mutations in the PCI gene in subfertile men.
The molecular aetiology of male subfertility is still unknown in the majority of cases and it is thought that multiple genes are involved. One of the genes that might play a role in male reproductive function is the protein C inhibitor (PCI) gene. In mice the presence of PCI is an absolute requirement for reproduction. In this study we performed a mutation screen of the PCI gene in subfertile m...
متن کاملRisk of testicular cancer in subfertile men: case-control study.
OBJECTIVE To evaluate the association between subfertility in men and the subsequent risk of testicular cancer. DESIGN Population based case-control study. SETTING The Danish population. PARTICIPANTS Cases were identified in the Danish Cancer Registry; controls were randomly selected from the Danish population with the computerised Danish Central Population Register. Men were interviewed ...
متن کاملGlycoprotein fucosylation is increased in seminal plasma of subfertile men.
Fucose, the monosaccharide frequent in N- and O-glycans, is a part of Lewis-type antigens that are known to mediate direct sperm binding to the zona pellucida. Such interaction was found to be inhibited in vitroby fucose-containing oligo- and polysaccharides, as well as neoglycoproteins. The objective of this study was to screen seminal plasma proteins of infertile/subfertile men for the conten...
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ژورنال
عنوان ژورنال: Fertility and Sterility
سال: 2017
ISSN: 0015-0282
DOI: 10.1016/j.fertnstert.2016.11.021