Outcomes of Steroid-Avoidance Protocols in Pediatric Kidney Transplant Recipients

Outcomes Associated with Steroid Avoidance and Alemtuzumab among Kidney Transplant Recipients.

BACKGROUND AND OBJECTIVES Alemtuzumab is a humanized anti-CD52 monoclonal antibody used as induction in kidney transplantation (KTX) since 2003. Few studies have evaluated long-term outcomes of this agent or changes in outcomes over time. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS A retrospective cohort study was performed examining United States registry data from 2003 to 2014 of primary ...

Very early steroid withdrawal or complete avoidance for kidney transplant recipients: a systematic review.

BACKGROUND The safety and efficacy of early steroid withdrawal or avoidance in patients receiving a kidney transplant (KT) are controversial. METHODS We performed a systematic review and a meta-analysis of the randomized controlled studies about steroid avoidance or withdrawal after a few days in patients receiving a KT and treated with antibody induction and cyclosporine (CsA) or tacrolimus ...

Covid-19 infection in kidney transplant recipients: a case report

[BK virus infections in pediatric kidney transplant recipients].

Primary BK virus (BKV) infections acquired mainly during childhood are usually asymptomatic. Several studies revealed its seroprevalence in adult population as high as 90% worldwide. Following primary infection, virus persists as latent infection in the urogenital tract. In renal transplant recipients, primary infection and reactivations affect 10% of patients and without treatment, more than h...

Cystatin C and renal function in pediatric kidney transplant recipients.

In clinical practice, the glomerular filtration rate (GFR) is often determined with serum creatinine. However, studies have shown cystatin C to be a better parameter for the diagnosis of impaired renal function. We compared GFR estimated by plasma cystatin C with GFR estimated by serum creatinine in a sample of 50 pediatric renal transplant recipients and 24 healthy children. The correlation be...