Ovariectomized Murine Model of Postmenopausal Calcium Malabsorption
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چکیده
منابع مشابه
Neuropharmacological properties of farnesol in Murine model
Research on new compounds of therapeutic value for behavioral disorders has progressed recently. Several studies have reported neuropharmacological activities of plant derived terpenes. Farnesol is a sesquiterpene whose most popular source is fruits but the anxiolytic activity for farnesol is still unknown. The present study was conducted on 32 male Swiss Albino mice (8 in each group) to evalua...
متن کاملOvariectomized rats as a model of postmenopausal osteoarthritis: validation and application
We aimed to assess the effect of ovariectomy on cartilage turnover and degradation, to evaluate whether ovariectomized (OVX) rats could form an experimental model of postmenopausal osteoarthritis. The effect of ovariectomy on cartilage was studied using two cohorts of female Sprague-Dawley rats, aged 5 and 7 months. In a third cohort, the effect of exogenous estrogen and a selective estrogen re...
متن کامل[Serum androgen concentrations and bone mineral density in postmenopausal ovariectomized and non-ovariectomized women].
OBJECTIVE Compare levels of androgens and bone mineral density (BMD) of ovariectomized (OVX) and non-ovariectomized (NOVX) postmenopausal women. Forty women, 20 OVX and 20 NOVX, (53.9 +/- 4 years) were selected. METHODS Total testosterone (TT), free testosterone (FT), androstenedione (AN), dehidroepiandrostenedione (DHEA) and its sulfate (DHEA-S) were measured. BMD was measured in 14 OVX and ...
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In postmenopausal women, reduced bone mineral density at the hip and spine is associated with an increased risk of tooth loss, possibly due to a loss of alveolar bone. In turn, having fewer natural teeth may lead to compromised food choices resulting in a poor diet that can contribute to chronic disease risk. The tight link between alveolar bone preservation, tooth retention, better nutritional...
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The pomegranate seed oil (PSO), containing 17-α-estradiol, is one of the newly found phytosterols with synergistic health effects on estrogen related physiological conditions. Herein, PSO was assessed for its potential improving effects on bone characteristics in a rat model of menopausal syndrome. Three month old non-pregnant female Wistar rats (n = 30) were either sham-operated (SHAM) or ovar...
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ژورنال
عنوان ژورنال: Journal of Bone and Mineral Research
سال: 1999
ISSN: 0884-0431
DOI: 10.1359/jbmr.1999.14.4.593