Overview of Basic Mechanisms of Cardiac Arrhythmia

Basic Mechanisms of Cardiac Arrhythmias1

An Overview of Calcium, Mechanisms and Necessities

Today, promoting quality of life and paying more attention to nutrition and health are among the major issues of international debate and governments' strategies to improve people's quality of life in different societies. There have also been extensive studies to improve nutrition and its relationship with health. The pattern of food consumption is different in most countries, different social ...

Species-Dependent Mechanisms of Cardiac Arrhythmia: A Cellular Focus

Although ventricular arrhythmia remains a leading cause of morbidity and mortality, available antiarrhythmic drugs have limited efficacy. Disappointing progress in the development of novel, clinically relevant antiarrhythmic agents may partly be attributed to discrepancies between humans and animal models used in preclinical testing. However, such differences are at present difficult to predict...

Unraveling the genetics and mechanisms of cardiac arrhythmia.

I this issue of the PNAS, Papadatos et al. (1) analyze the mechanism of arrhythmia in the heart after targeted disruption of the cardiac sodium channel, Scn5a. They combine a wide variety of techniques (including genetic deletion, cellular electrophysiology, morphology, and electrocardiography) in an integrated approach to unravel the sequence of events all of the way from the genetic to the wh...

Clinical Application and Functional Mechanisms of Intravenous Immunoglobulin: an Overview

Previous, Intravenous Immunoglobulin (IVIG) has been used for treatment of patients with immunodeficiency. However, recent studies have shown that IVIG is a suitable approach for treatment of inflammatory and autoimmune diseases. Although the exact mechanism of IVIG action is not well known, recent findings have demonstrated that IVIG impacts on expression and function of FC receptors of immuno...