Overweight and obesity associated with a missense polymorphism in fatty acid amide hydrolase (FAAH)

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Relation of C358A polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) with obesity and insulin resistance.

BACKGROUND AND AIMS Recently, it has been demonstrated that the polymorphism 385 C->A of FAAH (fatty acid amide hydrolase) was associated with overweight and obesity. The aim of our study was to investigate the relationship of missense polymorphism (cDNA 385 C-A) of FAAH gene on obesity anthropometric parameters, cardiovascular risk factors and adipocytokines. METHODS A population of 279 fema...

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ژورنال

عنوان ژورنال: International Journal of Obesity

سال: 2005

ISSN: 0307-0565,1476-5497

DOI: 10.1038/sj.ijo.0802954