Oxygen Is Instrumental for Biological Signaling: An Overview

Newest Targets for Anticonvulsant Agents: An Overview

Epilepsy is a neurological condition characterized by recurrent seizures influencing about 1% of the worldwide population. Despite much progress in understanding the pathogenesis of epilepsy, the molecular basis of human epilepsy still remains unclear. Common approaches for pharmacotherapy of epilepsy are still directed towards controlling the symptoms and suppression of seizures. Clinical use ...

Notch Signaling Pathway: An Overview

Pancreatic cancer is the most aggressive malignant disease once it is diagnosed and it remains the fourth leading cause of cancer-related death in the U.S.A. Recent data indicates that the Notch signaling pathway plays an important role in the development and progression of pancreatic cancer. Emerging evidence also suggests that the activation of the Notch signaling pathway is mechanistically a...

Biological Sequence Comparison: An Overview of Techniques

An Overview of Biological Macromolecule Crystallization

The elucidation of the three dimensional structure of biological macromolecules has provided an important contribution to our current understanding of many basic mechanisms involved in life processes. This enormous impact largely results from the ability of X-ray crystallography to provide accurate structural details at atomic resolution that are a prerequisite for a deeper insight on the way i...

IN-DEPTH REVIEW Biological hazards: an overview

The UK incidence of hepatitis B is falling. About 245 cases were reported per quarter in 1998-a marked decrease from just under 2000 reports in 1984. However, the prevalence remains high in other parts of the world and appreciably higher amongst healthcare workers. In Israel in 1994 the seroprevalence of anti-HBc was 10% in the general population but 24% in hospital employees; no significant ch...