Oxygenation-sensitive cardiovascular magnetic resonance

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Oxygenation-sensitive cardiovascular magnetic resonance

Oxygenation-sensitive cardiovascular magnetic resonance (CMR) is a non-contrast technique that allows the non-invasive assessment of myocardial oxygenation. It capitalizes on the fact that deoxygenated hemoglobin in blood can act as an intrinsic contrast agent, changing proton signals in a fashion that can be imaged to reflect the level of blood oxygenation. Increases in O(2) saturation increas...

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The impact of hematocrit on oxygenation-sensitive cardiovascular magnetic resonance

BACKGROUND Oxygenation-sensitive (OS) Cardiovascular Magnetic Resonance (CMR) is a promising utility in the diagnosis of heart disease. Contrast in OS-CMR images is generated through deoxyhemoglobin in the tissue, which is negatively correlated with the signal intensity (SI). Thus, changing hematocrit levels may be a confounder in the interpretation of OS-CMR results. We hypothesized that hemod...

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Impact of Intermittent Apnea on Myocardial Tissue Oxygenation—A Study Using Oxygenation-Sensitive Cardiovascular Magnetic Resonance

BACKGROUND Carbon dioxide (CO(2)) is a recognized vasodilator of myocardial blood vessels that leads to changes in myocardial oxygenation through the recruitment of the coronary flow reserve. Yet, it is unknown whether changes of carbon dioxide induced by breathing maneuvers can be used to modify coronary blood flow and thus myocardial oxygenation. Oxygenation-sensitive cardiovascular magnetic ...

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The relationship of hemoglobin concentration and signal intensity changes in oxygenation-sensitive cardiovascular magnetic resonance imaging

Background Oxygenation-sensitive cardiovascular magnetic resonance (OS-CMR) has become a feasible diagnostic imaging modality for monitoring changes of myocardial oxygenation. Yet, potential confounding factors of this technique are not well understood. Due to T2 effects caused by tissue water content, the hydration status may impact signal intensity. We aimed at quantifying the confounding eff...

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Physiological noise in oxygenation-sensitive magnetic resonance imaging.

The physiological noise in the resting brain, which arises from fluctuations in metabolic-linked brain physiology and subtle brain pulsations, was investigated in six healthy volunteers using oxygenation-sensitive dual-echo spiral MRI at 3.0 T. In contrast to the system and thermal noise, the physiological noise demonstrates a signal strength dependency and, unique to the metabolic-linked noise...

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ژورنال

عنوان ژورنال: Journal of Cardiovascular Magnetic Resonance

سال: 2013

ISSN: 1532-429X

DOI: 10.1186/1532-429x-15-43