Palladium–Protein Oxidative Addition Complexes by Amine-Selective Acylation
نویسندگان
چکیده
منابع مشابه
Enantioselective organocatalytic amine conjugate addition.
The first enantioselective organocatalytic amine conjugate addition has been successfully developed. The application of LUMO-lowering iminium catalysis has enabled the highly chemo- and enantioselective 1,4-addition of a rationally designed N-silyloxycarbamate nucleophile (HOMO-raised) to alpha,beta-unsaturated aldehydes. Imidazolidinone 2*pTSA was found to catalyze the addition of various orth...
متن کاملUnusual anti-selective asymmetric conjugate addition of aldehydes to nitroalkenes catalyzed by a biphenyl-based chiral secondary amine.
Unusual anti-selectivity was observed in the conjugate addition of aldehydes to nitroalkenes, when a biphenyl-based chiral secondary amine was used as catalyst.
متن کاملDetermination of Reaction Kinetic Parameters from Variable Temperature Kinetic Study for Oxidative Addition Reaction on Binuclear Cyclometalated Platinum(II) Complexes
The pseudo-first order rate constants and activation parameters have been determined using two methods, constant-temperature kinetic (CTK) and variable temperature kinetic (VTK), for the oxidative addition reactions of [Pt2Me2(C^N)2(µ-dppf)], (1a, C^N = deprotonated 2-phenylpyridine (ppy); 1b, C^N = deprotonated benzo[h]quinoline (bhq)) with MeI. The results obtained from VTK method are in agre...
متن کاملSelective precipitation of prions by polyoxometalate complexes.
The efficacy of a variety of polyoxometalate anions in selectively precipitating the infectious isoform of the prion protein (PrPSc) over the normal, cellular protein (PrPC) was tested as a means of improving the sensitivity of a conformation-dependent immunoassay (CDI). Experiments utilizing neutralized aqueous solutions containing MgCl2.6H2O and Na2H[PW12O40] (1) indicated that use of the for...
متن کاملCooperative bimetallic oxidative addition reactions*
The factors that control the oxidation of metals in bimetallic complexes are investigated in relation to the possibility of developing one-site addition two-metal oxidation reactions such as those that occur in the respiratory protein, hemerythrin. It is shown that the behavior of bimetallic complexes is not represented by the sum of the analogous monometallic parts because of metal and ligand ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 2020
ISSN: 0002-7863,1520-5126
DOI: 10.1021/jacs.0c09180