PAPAIN-INDUCED CHANGES IN RABBIT CARTILAGE
نویسندگان
چکیده
منابع مشابه
Papain-induced Changes in Rabbit Cartilage
Some biochemical aspects of the collapse of the rabbit ears produced by the intravenous injection of papain have been studied. A marked depletion of chondromucoprotein (M.C.S.) and a reduction of the S(35) content of cartilage matrix were found to coincide with the gross and histologic changes in the cartilage. At the same time there was a marked increase in the amount of S(35) in the serum and...
متن کاملPapain induced changes in cartilage.
I n tr o d u c tio n T E cfi'ccls o f the systemic adminis tration o f crude papain to young rabbits were first described by Thomas (1956), who noted that the most obvious change was a bilateral collapse o f the ears. This effect was lost within a few days. Subsequently llu lth and Westerborn (1959) and Merkow and Lalieh (1961), who iLsecl crude papain in single and repeated (loses, and in dif...
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objective: amiodarone as an iodinated benzofuran derivative is a potent antiarrhythmic agent currently used for the treatment of ventricular arrhythmias. pulmonary toxicity is one of the complications of amiodarone therapy. the aim of this study was to determine the toxicity of amiodarone for pneumocytes. materials and methods: 14 male white new zealand rabbits were divided in a control group a...
متن کاملThermoanalytical and histological study of intra-articular papain-induced degradation and repair of rabbit cartilage. II. Mature animals.
The effect of papain treatment on the cartilage tissue of the knee joint of mature rabbits was studied by histological and thermoanalytical methods. Changes taking place in the composition of cartilage in the course of ageing were shown. As a result of papain treatment a significant irreversible destruction of the ground substance took place. Papain-induced loss of proteoglycans and the intensi...
متن کاملCartilage matrix changes in contralateral mobile knees in a rabbit model of osteoarthritis induced by immobilization
BACKGROUND Many researches have investigated the changes associated with immobilization-induced osteoarthritis (OA). However, there are only few studies focusing on the effect of unilateral knee immobilization on cartilage matrix changes in the contralateral mobile knee. The aim of the present study was to investigate the influence of immobilization on the cartilage matrix in the contralateral ...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1958
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.108.4.507