Partial breast irradiation: Targeting volume or breast molecular subtypes?
نویسندگان
چکیده
منابع مشابه
Partial breast irradiation for early breast cancer.
BACKGROUND Breast conserving therapy for women with breast cancer consists of local excision of the tumour (achieving clear margins) followed by radiation therapy (RT). RT is given to sterilize tumour cells that may remain after surgery to decrease the risk of local tumour recurrence. Most true recurrences occur in the same quadrant as the original tumour. Whole breast RT may not protect agains...
متن کاملPartial-breast irradiation versus whole-breast irradiation for early-stage breast cancer: a cost-effectiveness analysis.
PURPOSE Accelerated partial-breast irradiation (PBI) is a new treatment paradigm for patients with early-stage breast cancer. Although PBI may lead to greater local recurrence rates, it may be cost-effective because of better tolerability and lower cost. We aim to determine the incremental cost-effectiveness of PBI compared with whole-breast radiation therapy (WBRT) for estrogen receptor-positi...
متن کاملAccelerated Partial Breast Irradiation and Hypofractionated Whole Breast Radiation
Breast conservation therapy (BCT), consisting of local excision of the breast tumor to achieve negative margins followed by whole breast irradiation, is standard treatment for early-stage breast cancer. The conventional radiotherapy course treats the entire breast, typically followed by a boost to the tumor bed over six to seven weeks. While the efficacy and cosmetic outcomes of conventionally ...
متن کاملAccelerated partial breast irradiation: potential roles following breast-conserving surgery.
BACKGROUND Multiple randomized trials comparing mastectomy to lumpectomy and whole breast irradiation (WBI) have shown equivalent survival outcomes in early-stage breast cancer. WBI requires a treatment course of several weeks, which has resulted in limited access to breast-conserving therapy in certain populations. A shorter accelerated course of partial breast irradiation (APBI) has been inve...
متن کاملAccelerated Partial Breast Irradiation in Clinical Practice.
Accelerated partial breast irradiation (APBI) has been under clinical investigation for more than 15 years. There are several technical approaches that are clinically established, e.g. brachytherapy, intraoperative radiotherapy (IORT), or external-beam radiotherapy. The understanding of the underlying biology, optimal technical procedures, patient selection criteria, and imaging changes during ...
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ژورنال
عنوان ژورنال: The Breast
سال: 2013
ISSN: 0960-9776
DOI: 10.1016/j.breast.2013.07.025