Partial-Volume Effect Correction Improves Quantitative Analysis of 18F-Florbetaben β-Amyloid PET Scans
نویسندگان
چکیده
منابع مشابه
Amyloid PET imaging in multiple sclerosis: an 18F-florbetaben study
BACKGROUND Positron emission tomography (PET) images with amyloid tracers show normal uptake in healthy white matter, which suggests that amyloid tracers are potentially useful for studying such white matter diseases as multiple sclerosis (MS). METHODS Twelve patients diagnosed with MS (5 with RRMS, 5 with SPMS, and 2 with PPMS) and 3 healthy controls underwent studies with MRI and (18)F-flor...
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We have developed, optimized, and validated a method for partial volume effect (PVE) correction of oncological lesions in positron emission tomography (PET) clinical studies, based on recovery coefficients (RC) and on PET measurements of lesion-to-background ratio (L/B m) and of lesion metabolic volume. An operator-independent technique, based on an optimised threshold of the maximum lesion upt...
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The partial volume effect in Positron Emission Tomography (PET) is a problem for quantitative radiotracer studies. This effect results from the limited spatial resolution of the imaging device (a few mm’s). Two factors are involved; the spillover of radioactivity into neighbouring regions and the underlying tissue inhomogeneity of the particular region. Linear methods are currently used to corr...
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ژورنال
عنوان ژورنال: Journal of Nuclear Medicine
سال: 2015
ISSN: 0161-5505,2159-662X
DOI: 10.2967/jnumed.115.161893