PARTICIPATION OF THE SYMPATHETIC NERVOUS SYSTEM IN SPONTANEOUSLY HYPERTENSIVE RATS
نویسندگان
چکیده
منابع مشابه
Nonselective Blocking of the Sympathetic Nervous System Decreases Detrusor Overactivity in Spontaneously Hypertensive Rats
The involuntary dual control systems of the autonomic nervous system (ANS) in the bladder of awake spontaneously hypertensive rats (SHRs) were investigated through simultaneous registrations of intravesical and intraabdominal pressures to observe detrusor overactivity (DO) objectively as a core symptom of an overactive bladder. SHRs (n = 6) showed the features of overactive bladder syndrome dur...
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To evaluate the effect of the sympathetic nervous system on radiation-induced apoptosis in jejunal crypt cells, apoptosis levels were compared in spontaneously hypertensive rats (SHR), animals which are a genetic hyperfunction model of the sympathetic nervous system, and normotensive Wistar-Kyoto rats (WKY). SHR and WKY were exposed to whole body X-ray irradiation at doses from 0.5 to 2 Gy. The...
متن کاملRecordings of renal and splanchnic sympathetic nervous activity in normotensive and spontaneously hypertensive rats.
1. Recordings have been obtained from single sympathetic fibres to the left kidney in anaesthetized adult spontaneously hypertensive (SH) rats and Wistar-Kyoto normotensive (WK) rats. 2. Under control conditions SH rats had a mean sympathetic activity of 3.3 +/- SE 0.45 Hz and WK rats 1.6 +/- 0.23 Hz. During noradrenaline infusion single fibre discharge decreased gradually to low levels in both...
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Although evidence exists for exaggerated sympathetic nervous system activity in spontaneously hypertensive rats (SHR), there are no studies in conscious animals that directly demonstrate that this increased activity is functionally involved in the elevated vascular resistance of these animals. In our present study, 8-week-old and 13-week-old SHR and Wistar Kyoto controls (WKY) were chronically ...
متن کاملLoss of accommodation in sympathetic neurons from spontaneously hypertensive rats.
Synaptic transmission and membrane properties of sympathetic neurons in superior cervical ganglia of spontaneously hypertensive rats (SHR), normotensive Wistar-Kyoto rats (WKY), and Sprague-Dawley rats (SD) were investigated in vitro by extracellular and intracellular recording. The sympathetic neurons of SHR showed an atypical loss of spike accommodation. The spike discharge was insensitive to...
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ژورنال
عنوان ژورنال: Japanese Circulation Journal
سال: 1973
ISSN: 0047-1828,1347-4839
DOI: 10.1253/jcj.37.609