Particle Size Distribution of HDL in Diabetics

HDL Particle Size and Functional Heterogeneity.

Classic clinical and epidemiological studies have long ago established the presence of an inverse relationship between high-density lipoprotein cholesterol (HDLC) levels and cardiovascular disease (CVD) risk, and thus, it was assumed that measures that increase HDLC levels would afford protection against atherosclerosis-based CVD. However, trials of drugs, such as cholesterol ester transfer pro...

Influence of apolipoprotein (Apo) A-I structure on nascent high density lipoprotein (HDL) particle size distribution.

The principal protein of high density lipoprotein (HDL), apolipoprotein (apo) A-I, in the lipid-free state contains two tertiary structure domains comprising an N-terminal helix bundle and a less organized C-terminal domain. It is not known how the properties of these domains modulate the formation and size distribution of apoA-I-containing nascent HDL particles created by ATP-binding cassette ...

Dynamic Evolution of Droplet/Particle Size Distribution in Suspension Polymerization of Styrene

Particle size distribution and particle mass measurements

Particle size distribution and particle mass measurements at urban, near-city and rural level in the Copenhagen area and Southern Sweden M. Ketzel , P. Wåhlin, A. Kristensson, E. Swietlicki, R. Berkowicz, O. J. Nielsen, and F. Palmgren Department of Atmospheric Environment, National Environmental Research Institute, Roskilde, Denmark Division of Nuclear Physics, Physics Department, Lund Univers...

HDL particle number and size as predictors of cardiovascular disease

Previous studies indicate that reduced concentrations of circulating high-density lipoprotein (HDL) particles can be superior to HDL-cholesterol (HDL-C) levels as a predictor of cardiovascular disease. Measurements of HDL particle numbers, therefore, bear a potential for the improved assessment of cardiovascular risk. Furthermore, such measurement can be relevant for the evaluation of novel the...