Patient-specific computational modeling of cortical spreading depression via diffusion tensor imaging
نویسندگان
چکیده
منابع مشابه
Stochastic modeling of spreading cortical depression
The nonlinear wave phenomenon of cortical spreading depression (SD), which occurs in many brain structures, has mathematical similarities to neuronal spiking but on very different space and time scales. Its properties and previous modeling are briefly reviewed. A model consisting of a 6-component reaction-diffusion system in two space dimensions is described. With 3-parameter Poisson process so...
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This preprint is made available because the published work cited below had several infelicities due to production error, i.e., awkward layout of equations and font styles. The conversion from the Words document here to IEEE TMI format was a mess. Abstract An analytical framework of error propagation for diffusion tensor imaging (DTI) is presented. Using this framework, any uncertainty of intere...
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Spreading cortical depression (SCD) is a wave of depolarization that spreads across the cortex at 2-5 mm/min and is followed by a 5-10 minute reduction in EEG activity. It is assumed that SCD is involved in the pathophysiology of migraine. We present a new model and a visualization technique for the spread of excitation on realistic brain surfaces. The usefulness of the technique is demonstrate...
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Editor's Note: These short, critical reviews of recent papers in the Journal, written exclusively by graduate students or postdoctoral fellows, are intended to summarize the important findings of the paper and provide additional insight and commentary. For more information on the format and purpose of the Journal Club, please see Review of Huang et al. Diffusion tensor imaging (DTI) is a robust...
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Introduction: Repetitive cortical spreading depression (CSD) can lead to cell death in immature brain tissue. Caspases are involved in neuronal cell death in several CSD-related neurological disorders. Yet, whether repetitive CSD itself can induce caspase activation in adult or juvenile tissue remains unknown. Inducing repetitive CSD in somatosensory cortices of juvenile and adult rats in vivo,...
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ژورنال
عنوان ژورنال: International Journal for Numerical Methods in Biomedical Engineering
سال: 2017
ISSN: 2040-7939
DOI: 10.1002/cnm.2874