Pattern Discovery in Genomic Coding Sequences Based on Protein Motifs
نویسندگان
چکیده
منابع مشابه
Prediction of Protein-Protein Interaction Based Only on Coding Sequences
Identification of the interactions among proteins is crucial to illustrate their functions, and further, can help to understand the biological processes and provide insights into the mechanisms of diseases. It has became one of the most challenging and important task in the postproteomic researches. Comparing with costly and time-consuming biochemical experiments, the computational methods have...
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Genome-wide multiple sequence alignments (MSAs) are a necessary prerequisite for an increasingly diverse collection of comparative genomic approaches. Here we present a versatile method that generates high-quality MSAs for non-protein-coding sequences. The NcDNAlign pipeline combines pairwise BLAST alignments to create initial MSAs, which are then locally improved and trimmed. The program is op...
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In molecular biology and bioinformatics, searching RNA gene occurrences in genomic sequences is a task whose importance has been renewed by the recent discovery of numerous functional RNA, often interacting with other ligands. Even if several programs exist for RNA motif search, no program exists that can represent and solve the problem of searching for occurrences of RNA motifs in interaction ...
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Motivation: Searching RNA gene occurrences in genomic sequences is a task whose importance has been renewed by the recent discovery of numerous functional RNA, often interacting with other ligands. Even if several programs exist for RNA motif search, no one exists that can represent and solve the problem of searching for occurrences of RNA motifs in interaction with other molecules. Results: We...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2012
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2011.11.1012