Pattern Recognition and Host Defense Response to Cryptococcus neoformans
نویسندگان
چکیده
منابع مشابه
Cryptococcus neoformans Is Resistant to Surfactant Protein A Mediated Host Defense Mechanisms
Initiation of a protective immune response to infection by the pathogenic fungus Cryptococcus neoformans is mediated in part by host factors that promote interactions between immune cells and C. neoformans yeast. Surfactant protein A (SP-A) contributes positively to pulmonary host defenses against a variety of bacteria, viruses, and fungi in part by promoting the recognition and phagocytosis of...
متن کاملMyD88 and TLR2, but not TLR4, are required for host defense against Cryptococcus neoformans.
We investigated here the potential role of Toll-like receptors (TLR) and the adaptor protein MyD88 in innate immunity responses to Cryptococcus neoformans, a pathogenic encapsulated yeast. Peritoneal macrophages from MyD88(-/-) or TLR2(-/-) mice released significantly less TNF-alpha, compared with wild-type controls, after in vitro stimulation with whole yeasts. In contrast, no differences in T...
متن کاملInsect immunity: from pattern recognition to symbiont-mediated host defense.
The Jacques Monod conference "Insect Immunity in Action: From Fundamental Mechanisms of Host Defense to Resistance Against Infections in Nature," organized by Ulrich Theopold (Stockholm University, Sweden) and Dominique Ferrandon (CNRS, France), was held in May 2009 in Aussois, France. Here, we review key topics and concepts that were presented and highlight emerging trends in the field of inse...
متن کاملTranscript analysis of some defense genes of tomato in response to host and non-host bacterial pathogens
The transcript levels of six defense genes including pathogenesis-related gene 1 (PR-1), pathogenesis-related gene 2 (PR-2), pathogenesis-related gene 5 (PR-5), lipoxygenase (LOX), phenylalanine ammonia-lyase (PAL) and catalase (CAT) were investigated in tomato plants inoculated with Xanthomonas axonopodis pv. phaseoli as a non-host pathogen and X. euvesicatoria as a host pathogen. Activation o...
متن کاملRegulation by innate immune T lymphocytes in the host defense against pulmonary infection with Cryptococcus neoformans.
Recently, innate immune lymphocytes, such as natural killer (NK) T cells and gamma/delta antigen receptor-bearing T (gamma delta T) cells, have garnered much attention, and their biological significance in the tumor immunity, allergic diseases and infectious diseases is extensively exploited. We have addressed the role of these cells in the host defense using a mouse model of pulmonary infectio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Medical Mycology Journal
سال: 2012
ISSN: 2185-6486,2186-165X
DOI: 10.3314/mmj.53.247