PB2370 CD34+ CELL COUNT BY FLOW CYTOMETRY IS BETTER THAN HEMATOPOIETIC PROGENITOR CELL COUNT BY SYSMEX XN ANALYZERS IN SAMPLES COLLECTED PRE-APHERESIS TO PREDICT APHERESIS PRODUCT STEM CELL YIELD
نویسندگان
چکیده
منابع مشابه
Large-volume leukapheresis in pediatric patients: pre-apheresis peripheral blood CD34+ cell count predicts progenitor cell yield.
BACKGROUND AND OBJECTIVE In children it is very important to optimize PBPC harvesting and to reduce the number of leukaphereses per patient. The value of pre-apheresis peripheral blood CD34+ cell concentration as a predictor of PBPC yield was studied in 23 pediatric patients with hematologic and non-hematologic malignancies in order to optimize duration of PBPC collection. DESIGN AND METHODS ...
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The Sysmex SE-9500 automated cell counter provides an estimate of immature cells referred to as 'haemopoietic progenitor cells' (HPC). The aim of this study was to relate the HPC count to CD34+ cell levels in mobilized peripheral blood and to determine whether the HPC count was valuable in predicting apheresis yields of CD34+ cells. Studies were performed on 114 samples from 67 patients undergo...
متن کاملIdentification of cell morphology parameters from automatic hematology analyzers to predict the peripheral blood CD34-positive cell count after mobilization
Optimal timing of apheresis initiation is important for maximizing the hematopoietic stem cell (HSC) yield. This study aimed to identify useful parameters from automatic hematology analyzers for predicting the peripheral blood CD34+ cell count after mobilization. We prospectively enrolled 53 healthy donors and 72 patients, and evaluated 43 cell morphology parameters from Unicel DxH800 (Beckman ...
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The gold standard to count circulating hematopoietic stem and progenitor cells (HPCs) is to enumerate CD34 cells by using flow cytometry [1, 2]. XE-2100 (Sysmex, Kobe, Japan), a currently used hematology analyzer, can be used to quantify HPCs, generating counts that reportedly correlate with those obtained using flow cytometric analysis of CD34 cells; however, XE-2100 HPC counts were 1.86-fold ...
متن کاملPediatric Hematopoietic Stem Cell Transplantation
The introduction and evolution of hematopoietic stem cell transplantation (HSCT) could be traced back to 1950s, to the studies on interactions among irradiation, covering spleen and bone marrow from it and injection of bone marrow cells. Today, HSCT is considered a well-established, effective and promising means of therapy for various malignant and non-malignant medical conditions, both in chil...
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ژورنال
عنوان ژورنال: HemaSphere
سال: 2019
ISSN: 2572-9241
DOI: 10.1097/01.hs9.0000567944.68727.c1