PDZBase: a protein-protein interaction database for PDZ-domains
نویسندگان
چکیده
منابع مشابه
PDZBase: a protein–protein interaction database for PDZ-domains
Summary: PDZBase is a database that aims to contain all known PDZ-domain-mediated protein–protein interactions. Currently, PDZBase contains approximately 300 such interactions, which have been manually extracted from >200 articles. The database can be queried through both sequence motif and keyword-based searches, and the sequences of interacting proteins can be visually inspected through align...
متن کاملPDZBase: a protein?Cprotein interaction database for PDZ-domains
SUMMARY PDZBase is a database that aims to contain all known PDZ-domain-mediated protein-protein interactions. Currently, PDZBase contains approximately 300 such interactions, which have been manually extracted from > 200 articles. The database can be queried through both sequence motif and keyword-based searches, and the sequences of interacting proteins can be visually inspected through align...
متن کاملRunning Title: PDZBase PDZBase: A protein-protein interaction database for PDZ-domains
Summary: PDZBase is a database that aims to contain all known PDZ-domain mediated protein-protein interactions. Currently, PDZBase contains approximately 300 such interactions, which have been manually extracted from >200 articles. The database can be queried through both sequence motif and keyword-based searches, and the sequences of interacting proteins can be visually inspected through align...
متن کاملUncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays.
One of the principal challenges in systems biology is to uncover the networks of protein-protein interactions that underlie most biological processes. To date, experimental efforts directed at this problem have largely produced only qualitative networks that are replete with false positives and false negatives. Here, we describe a domain-centered approach--compatible with genome-wide investigat...
متن کاملInteraction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein.
A novel protein, human X11-like (human X11L), contains a phosphotyrosine interaction (PI) domain and two PDZ domains and displays 55.2% amino acid homology with the human X11 (human X11). The PI domain of human X11L interacts with a sequence containing the NPXY motif found in the cytoplasmic domain of Alzheimer's amyloid precursor protein. A construct lacking the carboxyl-terminal domain, which...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2004
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/bti098