Penetration of Daptomycin into Bone and Synovial Fluid in Joint Replacement

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Penetration of daptomycin into bone and synovial fluid in joint replacement.

Daptomycin exhibits clinical activity in the treatment of infections with Gram-positive organisms, including infections due to methicillin-resistant Staphylococcus aureus. However, little is known about its penetration into bone and synovial fluid. The aim of our study was to assess the penetration of daptomycin into bone and synovial fluid after a single intravenous administration. This study ...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 2014

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.02344-14