PEPstrMOD: structure prediction of peptides containing natural, non-natural and modified residues
نویسندگان
چکیده
منابع مشابه
Natural peptides and proteins: potent tyrosinase inhibitors
Background and objectives: Tyrosinase is a copper containing oxidase which is crucial for controlling the production of melanin in creatures such as bacteria, fungi, plants and mammals. It is involved in the first two steps of melanin biosynthesis and leads to pigmentation and different types of cancer such as melanoma. Also, it is responsible for browning of fruits and vegetab...
متن کاملPorous structure of natural and modified clinoptilolites.
The evaluation of the pore-size distribution (PSD) of natural and modified mesoporous zeolites, i.e., clinoptilolites is presented. We demonstrate the SEM results showing that the pores of fracture-type from 25-50 nm to 100 nm in size between clinoptilolite grains, as well as pores between crystal aggregates up to 500 nm in size are present in the studied material. The detailed distribution of ...
متن کاملThe synthesis of peptides and proteins containing non-natural amino acids.
Methods for the incorporation of non-natural amino acids into proteins have advanced significantly over recent years and in this tutorial review we aim to give a general overview of the area. These techniques offer the possibility of modulating the structures and functions of proteins and thus permit the generation of novel designed systems for both biocatalytic and mechanistic studies. Four co...
متن کاملStructure and Properties of a Natural Celulosic Hollow Fiber
The interaction of thermal radiation with conduction and laminar natural convection in a vertical circular pin, situated at participating gas, is numerically investigated. An absorbing and emitting gas is considered, and treated to be a gray participating media. Under the idealizing of gray gas, the Rosselan4 approximation is employed to describe the radiative heat flux in the energy equation. ...
متن کاملStructure-Based Design of Non-natural Macrocyclic Peptides That Inhibit Protein–Protein Interactions
Macrocyclic peptides can interfere with challenging biomolecular targets including protein-protein interactions. Whereas there are various approaches that facilitate the identification of peptide-derived ligands, their evolution into higher affinity binders remains a major hurdle. We report a virtual screen based on molecular docking that allows the affinity maturation of macrocyclic peptides t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biology Direct
سال: 2015
ISSN: 1745-6150
DOI: 10.1186/s13062-015-0103-4