Perfusion-CT: A Non-Invasive Tool to Monitor Regional Brain Perfusion in Traumatic Brain Injury Patients and Therapies Impacting it

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Perfusion-CT: A Non-Invasive Tool to Monitor Regional Brain Perfusion in Traumatic Brain Injury Patients and Therapies Impacting it

There is a growing body of evidence suggesting imaging biomarkers to select patients with traumatic brain injury (TBI) for therapies, and to monitor the effects of these treatments. In this setting, advanced neuroimaging techniques such as perfusion-CT (PCT) can offer more clinically relevant pathophysiologic information than purely structural imaging such as conventional noncontrast CT. Patien...

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The pattern of brain perfusion SPECT in non-medicated schizophrenic patients

  Introduction: Studies with single photon emission computed tomography (SPECT) have revealed inconsistent changes of regional cerebral blood flow (rCBF) in schizophrenia. Some studies investigated the rCBF and its relationship with psychopathology, positive and negative symptoms in treated patients. However, there is a little information about the pattern of rCBF in ...

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Early Cerebral Circulation Disturbance in Patients Suffering from Severe Traumatic Brain Injury (TBI): A Xenon CT and Perfusion CT Study

Traumatic brain injury (TBI) is widely known to cause dynamic changes in cerebral blood flow (CBF). Ischemia is a common and deleterious secondary injury following TBI. Detecting early ischemia in TBI patients is important to prevent further advancement and deterioration of the brain tissue. The purpose of this study was to clarify the cerebral circulatory disturbance during the early phase and...

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Pathophysiological Concepts in Mild Traumatic Brain Injury: Diffusion Tensor Imaging Related to Acute Perfusion CT Imaging

BACKGROUND A subgroup of patients with mild traumatic brain injury (TBI) experiences residual symptoms interfering with their return to work. The pathophysiological substrate of the suboptimal outcome in these patients is a source of debate. OBJECTIVE To provide greater insight into the pathophysiological mechanisms of mild TBI. METHODS Diffusion tensor imaging (DTI) was performed during fo...

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ژورنال

عنوان ژورنال: The Open Neurosurgery Journal

سال: 2010

ISSN: 1876-5297

DOI: 10.2174/1876529701003010059