Peri-partum reference ranges for ROTEM ® thromboelastometry

Thromboelastometry (ROTEM) in children: age-related reference ranges and correlations with standard coagulation tests.

BACKGROUND The small sample volume needed and the prompt availability of results make viscoelastic methods like rotational thromboelastometry (ROTEM) attractive for monitoring coagulation in small children. However, data on reference ranges for ROTEM parameters in children are scarce. METHODS Four hundred and seven children (ASA I and II) undergoing elective surgery were recruited for this pr...

Reference ranges for rotational thromboelastometry in male Sprague Dawley rats

Background A functional coagulation assay was used to investigate the extrinsic pathway of coagulation on citrated whole blood samples from healthy adult male Sprague Dawley rats using the mini cup and pin system. Methods Reference values for coagulation parameters from forty-three animals were calculated using data obtained from the ROTEM® delta hemostasis analyzer with the EXTEM test. Res...

Rotation thromboelastometry (ROTEM) stability and reproducibility over time.

BACKGROUND Thromboelastometry is a whole blood assay performed to evaluate the viscoelastic properties during blood clot formation and lysis. Rotation thromboelastography (ROTEM), Pentapharm GmbH, Munich, Germany) has overcome some of the limitations of classic thromboelastography. So far, no clinical validation on reproducibility (inter- and intra-assay variability) and sample stability over t...

Rotational thromboelastometry (ROTEM®) – targeted therapy for coagulation management in patients with massive bleeding

Comparison of fibrin-based clot elasticity parameters measured by free oscillation rheometry (ReoRox®) versus thromboelastometry (ROTEM®)

BACKGROUND Whole blood viscoelastic tests such as the fibrin-based thromboelastometry (ROTEM(®)) test FIBTEM are increasingly used in the perioperative setting to quickly identify deficits in fibrin quality, and to guide hemostatic therapy. The recently developed FibScreen2 test of the ReoRox(®) method, based on free oscillation rheometry, also provides an evaluation of fibrin clot quality. To ...