Peripheral nerve entrapment: An unusual adverse event with high-dose interleukin-2 therapy
نویسندگان
چکیده
منابع مشابه
Peripheral nerve entrapment: an unusual adverse event with high-dose interleukin-2 therapy.
Recombinant interleukin 2 (rIL-2) is a promising biological therapy agent in the treatment of patients with metastatic renal cell carcinoma and metastatic melanoma [1, 2]. The antitumor effects are a result of a complex interplay of generation of NK and T-cells and secretion of a variety of lymphokines (IFN, IL6 and TNF) [3]. Early studies and success with rIL-2 were reported with the high dose...
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Peripheral nerve entrapment lesions are common clinical disorders. Despite this fact, many neurosurgeons do not have vast training or experience in the diagnosis and management of patients with peripheral nerve entrapments or do not treat these patients because of lack of interest or referral patterns. There are many other reasons to develop a niche for this area of neurosurgery and to incorpor...
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Although high-dose interleukin-2 (IL-2, Proleukin), a highly toxic agent used in the treatment of renal cell carcinoma and melanoma, was initially associated with treatment-related mortality, it can, in the appropriate setting, be administered safely. High-dose IL-2 is associated with significant morbidity; however, the incidence and severity of toxicities have decreased as clinicians have gain...
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High-dose interleukin-2 (IL-2) is an available treatment option for patients with metastatic melanoma or renal cell carcinoma, and is associated with sustained complete and partial responses in a subset of patients. IL-2, however, is not devoid of toxicities, most of which involve the cardiovascular system and manifest as hypotension, arrhythmias, and cardiomyopathy. This report describes an un...
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A 37 year old white woman with a well-known history of migraine headaches presented to an urgent care center with a chief complaint of severe headache with associated nausea that was unrelieved by medication that she had at home. She had taken Axert® (almotriptan) at home and repeated it once, without any improvement in her symptoms; she typically had good results with this medication. Upon pre...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 1996
ISSN: 0923-7534
DOI: 10.1093/oxfordjournals.annonc.a010647