Phenylbutazone and flunixin meglumine used singly or in combination in experimental lameness in horses

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Phenylbutazone and flunixin meglumine used singly or in combination in experimental lameness in horses.

REASON FOR PERFORMING STUDY Using an adjustable heart bar shoe model of foot pain, the objective of this study was to test the hypothesis that the combined use of phenylbutazone (PBZ) and flunixin meglumine (FM) would prove more efficacious in alleviating lameness than either drug alone. MATERIALS AND METHODS One hour after induction of lameness at weekly intervals, 8 healthy adult Thoroughbr...

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Effects of flunixin meglumine on experimental tendon wound healing: A histopathological and mechanical study in rabbits

Tendons are frequently targets of injury in sports and work. Whether nonsteroidal anti-inflammatory drugs (NSAIDs) have beneficial effects on tendon healing is still a matter of debate. This study was conducted to evaluate effects of flunixin meglumine (FM) on tendon healing after experimentally induced acute trauma. Twenty eight adult male New Zealand White rabbits were subjected to complete t...

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This study was designed to evaluate the toxicity of flunixin meglumine, a nonsteroidal anti-inflammatory drug which might serve as an alternate of diclofenac that has been shown to cause toxicity in vultures. Twenty five broiler chickens of five weeks of age were randomly divided into five equal groups and treated with flunixin meglumine at the dosage rate of 0, 1.25, 2.5, 5 and 10 mg/kg body w...

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FLUNIXIN MEGLUMINE Flunixin meglumine (Banamine) is frequently used in horses for the treatment of colic and endotoxemia. It has not historically been used for treating lameness, due to a perceived inferiority to phenylbutazone for musculoskeletal pain. Comparative studies in horses with naturally occurring navicular disease have shown no significant differences in the analgesic effects of flun...

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ژورنال

عنوان ژورنال: Equine Veterinary Journal

سال: 2011

ISSN: 0425-1644

DOI: 10.1111/j.2042-3306.2011.00485.x