Phospholipase C Mediated Modulation of TRPV1 Channels
نویسندگان
چکیده
منابع مشابه
Monoacylglycerols Activate TRPV1 – A Link between Phospholipase C and TRPV1
Phospholipase C-mediated hydrolysis of phosphatidylinositol 4,5-bisphosphate generates diacylglycerol, inositol 1,4,5-trisphosphate and protons, all of which can regulate TRPV1 activity via different mechanisms. Here we explored the possibility that the diacylglycerol metabolites 2-arachidonoylglycerol and 1-arachidonoylglycerol, and not metabolites of these monoacylglycerols, activate TRPV1 an...
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ژورنال
عنوان ژورنال: Molecular Neurobiology
سال: 2008
ISSN: 0893-7648,1559-1182
DOI: 10.1007/s12035-008-8027-y