Physical crosslinking modulates sustained drug release from recombinant silk-elastinlike protein polymer for ophthalmic applications
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چکیده
منابع مشابه
Silk fibroin microparticles as carriers for delivery of human recombinant BMPs. Physical characterization and drug release.
Bone morphogenetic proteins (BMPs) are cytokines with strong ability to promote new bone formation. Herein, we report the use of silk fibroin microparticles as carriers for the delivery of BMP-2, BMP-9 or BMP-14. BMP-containing fibroin microparticles were prepared by a mild methodology using dropwise addition of ethanol, exhibiting mean diameters of 2.7 +/- 0.3 microm. Encapsulation efficiencie...
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ژورنال
عنوان ژورنال: Journal of Controlled Release
سال: 2011
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2011.07.036