Physiological functions and pathogenic potential of uric acid: A review
نویسندگان
چکیده
منابع مشابه
Physiological functions and pathogenic potential of uric acid: A review
Uric acid is synthesized mainly in the liver, intestines and the vascular endothelium as the end product of an exogenous pool of purines, and endogenously from damaged, dying and dead cells, whereby nucleic acids, adenine and guanine, are degraded into uric acid. Mentioning uric acid generates dread because it is the established etiological agent of the severe, acute and chronic inflammatory ar...
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In order to survive in an oxygen environment, aerobic organisms have developed numerous mechanisms to protect against oxygen radicals and singlet oxygen. One such mechanism, which appears to have attained particular significance during primate evolution, is the direct scavenging of oxygen radicals, singlet oxygen, oxo-haem oxidants and hydroperoxyl radicals by uric acid. In the present paper we...
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ژورنال
عنوان ژورنال: Journal of Advanced Research
سال: 2017
ISSN: 2090-1232
DOI: 10.1016/j.jare.2017.03.003