Phytochemical test and identification of active compounds with LC-MS/MS in green meniran leaf (Phyllanthus niruri Linn)

نویسندگان

چکیده

Background: Green meniran plant (Phyllanthus niruri Linn) is traditionally believed to treat many diseases, such as reducing fever, diarrhea, cough with phlegm, inflammation, malaria, and acne. This research aims determine the class of compounds active in ethanol extract green leaf.Methods: An experimental study was conducted using phytochemical testing includes qualitative quantitative tests identify leaf by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). Crude powder packaging at Materia Medika Herbal Laboratory, Malang, Indonesia. The extraction from Pharmacology Faculty Mathematics Natural Sciences, Udayana University.Results: Based on results test, positive for flavonoids, saponins, steroids, terpenoids, alkaloids, phenols, tannins, glycosides. From tests, we found levels phenolic, flavonoid, tannin 5.13%, 3.30%, 5.01%, respectively 28.212.67 mg/kg chlorophyll. Identification LC-MS/MS showed suspected Apigenin-8-C-glucoside glycoside group 5,6,7-trimethoxyflavone flavonoid group.Conclusion: contains glycosides 5,6,7-trimethoxyflavone.

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ژورنال

عنوان ژورنال: Bali Medical Journal

سال: 2021

ISSN: ['2089-1180', '2302-2914']

DOI: https://doi.org/10.15562/bmj.v10i1.2208