Pimecrolimus Cream 1% in the Management of Atopic Dermatitis in Pediatric Patients: A Meta-Analysis
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چکیده
منابع مشابه
Pimecrolimus Cream 1% in the Management of Atopic Dermatitis in Pediatric Patients: A Meta-Analysis
OBJECTIVE To evaluate the efficacy and safety of pimecrolimus cream 1% in the treatment of AD in the pediatric population. METHODS PubMed, EMBASE, Web of Science and Cochrane library databases were searched till July 2013. The randomized and nonrandomized blinded studies of pimecrolimus cream 1% applied twice daily with Jaded score ≥ 3 in pediatric patients with AD were included. The efficacy...
متن کاملRetraction: Pimecrolimus Cream 1% in the Management of Atopic Dermatitis in Pediatric Patients: A Meta-Analysis
After the publication of the article, a group of readers raised concerns about several aspects of the methodology for the metaanalysis and the interpretation of the results (http://www.plosone. org/article/comments/info%3Adoi%2F10.1371%2Fjournal.pone. 0093095). Upon follow-up with the authors and consultation with editorial board members, the following concerns have been identified: * The inter...
متن کاملPimecrolimus 1% cream (Elidel) for atopic dermatitis.
Pimecrolimus is an immunomodulating medication that inhibits production of inflammatory cytokines in the skin and this compound was specifically developed for the treatment of inflammatory skin diseases. Phase II and III clinical trials with the topical formulation of pimecrolimus (Elidel cream, Novartis) have shown that it is safe and effective for use in patients with atopic dermatitis (AD). ...
متن کاملPimecrolimus cream in the management of patients with atopic eczema
Atopic eczema is a common pediatric skin disorder. This review examines the use of pimecrolimus cream in the treatment of acute and chronic stages of the disease. The standard therapy is the treatment of acute flares with topical medications including pimecrolimus. The use of pimecrolimus cream for the first sign and symptoms of atopic eczema reduces the occurrence of flares as defined by the n...
متن کاملSystemic exposure, tolerability, and efficacy of pimecrolimus cream 1% in atopic dermatitis patients.
AIMS To measure pimecrolimus blood concentrations and to evaluate tolerability and efficacy in children and infants treated topically for atopic dermatitis with pimecrolimus cream 1% for three weeks. METHODS Three open label, non-controlled, multiple topical dose studies were conducted in children aged 8-14 years (study A, ten patients), and in infants aged 8-30 months (study B, eight patient...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0093095