Planar Cell Polarity Signaling in Collective Cell Movements During Morphogenesis and Disease
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چکیده
منابع مشابه
Planar Cell Polarity Signaling in Collective Cell Movements During Morphogenesis and Disease
Collective and directed cell movements are crucial for diverse developmental processes in the animal kingdom, but they are also involved in wound repair and disease. During these processes groups of cells are oriented within the tissue plane, which is referred to as planar cell polarity (PCP). This requires a tight regulation that is in part conducted by the PCP pathway. Although this pathway w...
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Epithelial cells and other groups of cells acquire a polarity orthogonal to their apical-basal axes, referred to as Planar Cell Polarity (PCP). The process by which these cells become polarized requires a signaling pathway using Frizzled as a receptor. Responding cells sense cues from their environment that provide directional information, and they translate this information into cellular asymm...
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ژورنال
عنوان ژورنال: Current Genomics
سال: 2012
ISSN: 1389-2029
DOI: 10.2174/138920212803759721