Plasma coagulation factor VII activity and its correlates in healthy men
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Original Contributions Factor VII Coagulant Activity and Antigen Levels in Healthy Men Are Determined by Interaction Between Factor VII Genotype and Plasma Triglyceride Concentration
Ischemic heart disease is caused by a combination of and interaction between a number of genetic and environmental factors. In a study of a group of healthy men from the United Kingdom, such an interaction was identified between the levels of plasma triglycerides and genetic variation determining plasma levels of factor VII, a clotting factor that is associated with risk of ischemic heart disea...
متن کاملFactor VII coagulant activity and antigen levels in healthy men are determined by interaction between factor VII genotype and plasma triglyceride concentration.
Ischemic heart disease is caused by a combination of and interaction between a number of genetic and environmental factors. In a study of a group of healthy men from the United Kingdom, such an interaction was identified between the levels of plasma triglycerides and genetic variation determining plasma levels of factor VII, a clotting factor that is associated with risk of ischemic heart disea...
متن کاملEffect of individual dietary fatty acids on postprandial activation of blood coagulation factor VII and fibrinolysis in healthy young men.
BACKGROUND Hypertriglyceridemia may represent a procoagulant state involving disturbances to the hemostatic system. Plasminogen activator inhibitor type 1 (PAI-1) is increased in the presence of hypertriglyceridemia. Free fatty acids (FFAs) in plasma may promote factor VII (FVII) activation. OBJECTIVE We tested the hypothesis that FVII activation would be less after consumption of saturated f...
متن کاملPlasma fibrinogen and its correlates in urban Japanese men.
BACKGROUND The intention of the study was to examine determinants of plasma fibrinogen concentrations in Japanese men. METHODS A cross-sectional study was conducted in 1991 among 995 male employees aged 40-59 years in two urban companies. RESULTS The overall mean value (standard deviation) of plasma fibrinogen concentration was 257 (57) mg/dl. There was a strong dose-response relationship b...
متن کاملAre there any associations among coagulation factor VII gene polymorphism, plasma activated factor VII levels, and cerebrovascular disease?
Factor VII Gene Polymorphism, Plasma Activated Factor VII Levels, and Cerebrovascular Disease? To the Editor: We read with interest the article by Ghaddar et al1 showing no association of subclinical atherosclerosis with plasma coagulation factor VII (FVII) level or with FVII gene polymorphism (FVII R353Q), both of which were reported to be associated with myocardial infarction in whites.2,3 Th...
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ژورنال
عنوان ژورنال: European Journal of Clinical Nutrition
سال: 2005
ISSN: 0954-3007,1476-5640
DOI: 10.1038/sj.ejcn.1602257