Plasma-insulin-cognizant adaptive model predictive control for artificial pancreas systems
نویسندگان
چکیده
منابع مشابه
Artificial Pancreas Based on Model Predictive Control
Diabetes is recognized as a group of heterogeneous disorders with the common elements of high blood glucose concentration and glucose intolerance, due to insulin deficiency and impaired effectiveness of insulin action. The most common types of diabetes are diabetes mellitus type 1 and diabetes mellitus type 2, which does not necessarily require insulin injections. Type 2 constitutes about 85 to...
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BACKGROUND The objective of this research is to develop a new artificial pancreas that takes into account the experience accumulated during more than 5000 h of closed-loop control in several clinical research centers. The main objective is to reduce the mean glucose value without exacerbating hypo phenomena. Controller design and in silico testing were performed on a new virtual population of t...
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Model predictive controller is widely used in industrial plants. Uncertainty is one of the critical issues in real systems. In this paper, the direct adaptive Simplified Model Predictive Control (SMPC) is proposed for unknown or time varying plants with uncertainties. By estimating the plant step response in each sample, the controller is designed and the controller coefficients are directly ca...
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A Constrained Model Predictive Control (CMPC) approach for regulating blood-glucose levels in people with type 1 Diabetes is proposed. The controller uses the past suggested insulin, the subcutaneous glucose level, and an estimation of the carbohydrate amount of the future meals provided by the patient as inputs to decide the quantity of insulin to inject by a subcutaneous pump. This strategy a...
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The relative merits of model predictive control (MPC) and proportional-integral-derivative (PID) control are discussed, with the end goal of a closed-loop artificial pancreas (AP). It is stressed that neither MPC nor PID are single algorithms, but rather are approaches or strategies that may be implemented very differently by different engineers. The primary advantages to MPC are that (i) const...
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ژورنال
عنوان ژورنال: Journal of Process Control
سال: 2019
ISSN: 0959-1524
DOI: 10.1016/j.jprocont.2019.03.009